HLA-12

HLA

HLA12

	CODE	PROBE	ACC.N	MAP	UCSC May 2004	REMARKS
	7A	RP11-713A20	AC093686	7p22.3	chr7:106,471-298,664
	7B	RP11-745M18	AC092488	7p22.3	chr7:2,324,670-2,416,104	HLA12p& 1p
B-A						HyA translocation
	2S	RP11-717H1	BES	2q23.2	chr2:150,112,110-150,286,763	HLA12p& 1p
	2R	RP11-107E5	AC010090	2q22.3	chr2:145,157,861-145,273,457
	2Q	RP11-135M24	BES	2q21.2	chr2:133,244,529-133,391,652
B-H
		RP11-243I5	BES	2q14.1	chr2:114,221,969-114,408,721	12p&crosshyb
	2N	RP11-475I16	AC010982	2q14.1	chr2:114,470,625-114,687,731
	2O	RP11-438O12	AC012363	2q14.2	chr2:120,629,082-120,846,427
		RP11-333J2	AC097499	2q14.3	chr2:126,163,856-126,357,828
	2P	RP11-135O12	BES	2q21.1	chr2:131,439,791-131,615,188
		Ancestral Centromere			chr2:131,874,851-132,800,127
			NOR
			CENTROMERE
B-L						HLA fusion
	8E	RP11-1144H24	BES	8p11.1	chr8:43,724,198-43,872,082
		RP11-10D7	AC013603	8p12	chr8:33,487,657-33,665,495
	8D	RP11-583M2	AC051642	8p21.2	chr8:23,420,721-23,595,169
		RP11-946C22	BES	8p21.3	chr8:19,927,556-20,161,490
	8C	RP11-908D16	BES	8p21.3	chr8:19,831,557-20,005,388	HLA12q&7q
B-A						HyA translocation
	3C	RP11-381E19	BES	3p24.3	chr3:19,684,916-19,856,368	HLA12q&7q
		RP11-321I9	BES	3p25.1	chr3:15,196,587-15,384,665
	3B	RP11-1136I4	BES	3p25.1	chr3:15,046,733-15,198,512	HLA12q&crossybr
B-H
	3N	RP11-787P10	BES	3q21.3	chr3:131,347,372-131,500,320	HLA12q&crossybr
		RP11-21N8	AC023438	3q21.3	chr3:131,810,604-131,961,221
		RP11-160C8	BES	3q22.3	chr3:145,982,556-146,127,423
	3O	RP11-640P20	BES	3q24	chr3:147,421,551-147,605,803	HLA12q&crossybr
B-A						HyA translocation
	12F	RP11-23J18	BES	12q13.11	chr12:45,755,429-45,925,226	HLA12qter&10q
	12G	RP11-95A3		12q13.13	chr12:50,596,817-50,769,060

Legend. HLA ideogram (left) showing the synteny block correspondence with the human chromosome(s) (right). Internal red numbers indicate the human corresponding chromosome. Blue and red arrows indicate concordant (blue) and inverse (red) sequence polarity (orientation) with respect to humans. Black numbers (chromosome) followed by a letter (BAC), on the right, indicate specific BACs as reported in the Supplemental Table S1.

B-H Breaks in lineages leading to HSA	B-L Breaks in lineages leading to Lar	HyA: Hylobatidae ancestor
B-A Breaks in hylobatidae ancestor	B-N Breaks in lineages leading to Nomascus	Splitting clones

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