HLA-3

HLA

HLA3

	CODE	PROBE	ACC.N	MAP	UCSC May 2004	REMARKS
	6M	RP11-302L19	AL596442	6q27	chr6:170,340,087-170,450,903
	6L	RP11-437I16	AL450340	6q21	chr6:106,255,373-106,319,178
	6K	RP11-469L14	BES	6q14.3	chr6:86,020,570-86,185,023	HLA3p&3q
B-A						HyA inversion&fission
		CENTROMERE				Neocentromere in HyA
	6F	RP11-346L9	BES	6p11.2	chr6:57,351,232-57,548,984	HLA3q&20p
		RP11-799H20	BES	6p11.2	chr6:57,787,081-58,000,708
	6G	RP11-484F20	BES	6p11.2	chr6:58,720,610-58,883,743
		HSA Centromere			chr6:58,888,126-58,938,125
	6H	RP11-1087D10	AQ718724	6q12	chr6:64,775,570-64,989,766
		RP11-387L5	AL512368	6q12	chr6:68,415,086-68,562,704
	6I	RP11-23H8		6q14.1	chr6:78,815,463-78,961,907
	6J	RP11-615P21		6q14.1	chr6:78,903,365-79,106,038
	6K	RP11-469L14	BES	6q14.3	chr6:86,020,570-86,185,023	HLA3p&3q
B-L						Fusion in HLA relic of cen?
B-L						Fusion in HLA relic of cen?
	4D	RP11-845G8	AQ791487	4q11	chr4:52,562,701-52,738,879
	4E	RP11-245E9	BES	4q11	chr4:69,547,000-69,700,016
	4F	RP11-915G24	BES	4q13.2	chr4:69,789,054-69,958,759
		RP11-458G13	BES	4q21.23-21.3	chr4:87,213,874-87,384,889
	4G	RP11-499E18	AC098487	4q24	chr4:103,572,839-103,736,754
	4H	RP11-1091M15	BES	4q25	chr4:110,517,162-110,721,162	HLA2q&3q
B-A	NLE	CH271-138C4	BES		chr4:110,472,197/chr10:23,987,314	HyA translocation HLA3q
	10B	RP11-344N19	BES	10p12.2	chr10:23,942,660-24,115,999	HLA3q&2q
		RP11-368M8	AQ528054	10p12.2	chr10:22,833,626-23,007,256
	10A	RP11-363N22	AL359878	10p15.3	chr10:854,871-1,039,159

Legend. HLA ideogram (left) showing the synteny block correspondence with the human chromosome(s) (right). Internal red numbers indicate the human corresponding chromosome. Blue and red arrows indicate concordant (blue) and inverse (red) sequence polarity (orientation) with respect to humans. Black numbers (chromosome) followed by a letter (BAC), on the right, indicate specific BACs as reported in the Supplemental Table S1.

B-H Breaks in lineages leading to HSA	B-L Breaks in lineages leading to Lar	HyA: Hylobatidae ancestor
B-A Breaks in hylobatidae ancestor	B-N Breaks in lineages leading to Nomascus	Splitting clones

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