Synteny block organization of

Chlorocebus aethiops, CAE (Vervet; 2n=60)

(as part of the vervet genome project)

CAE karyotype

CAE synteny blocks arrangement with respect to HSA (summary)

CAE chromosome organization with respect to HSA. Each page shows, at bottom, the evolutionary history of the chromosome with respect to the Catarrhini ancestor (Stanyon et al., 2012§)
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9

* chromosomes harboring a nentromere not present in the common ancestor of Cercopithecoidea (OWM).

Human chromosomes contributing to each CAE chromosome
CAE
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10
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12
13
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18
 19 20 21 22 23 24 25 26 27 28 29
HSA 11 20
21
 13 5 16 19 4 8 10 2 12 9 6 2 3 17 6 18 22 1 7 3 5 14 1 15 4 7 14
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CAE chromosomes contributing to each human chromosome
HSA
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2
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18
 19 20 21 22
CAE 20
25
 10
14
 15
22
 7
27
 4
23
 13
17
 21
28
 8 12 9 1 11 3 24
29
 26
29
 5 16 18 6 2 2 19

The synteny blocks arrangement of vervet chromosomes (excel file) was defined by cohybridization FISH experiments using ~500 human BAC clones scattered on the vervet genome. Their position on the human sequence was derived from the UCSC browser (hg19). Each breakpoint was determined by reiterative FISH experiments aimed at narrowing the interval containing the break. For breakpoints shared with macaque, we took advantage of the FISH experiments previously performed on this species (see http://www.biologia.uniba.it/macaque2013).

§ Stanyon R, Rocchi M, Bigoni F, Archidiacono N: Evolutionary molecular cytogenetics of catarrhine primates: past, present and future. Cytogenet Genome Res, 137:273-284 (2012)