inv(16) involving CBFB and MYH11 genes

  CBFB

Probes donated by Dr. Peter Marynen (Peter.Marynen@med.kuleuven.ac.be)
PAC	position	FISH on metaphases or nuclei from:	comments
dJ20A14	16q22	M4eo-ANLL patien [inv(16) case 1]	centromeric to the b.p.
dJ8F4	16q22	M4eo-ANLL patient [inv(16) case 1]	SPLITS (bigger signal centromeric to the breakpoint) *
dJ559N16	16q22	M4eo-ANLL patient [inv(16) case 1]	centromeric to the b.p.

  MYH11

PAC	position	FISH on metaphases or nuclei from:	comments
dJ1114C15	16p13	M4eo-ANLL patien [inv(16) case 1]	SPLITS (bigger signal centromeric to the breakpoint)

  Cohybridization experiments

PROBES	FISH on metaphases or nuclei from:	comments
dJ1032E3C (16p)+   CBFBF (16q)	M4eo-ANLL patien [inv(16) case 1]	OK in metaphases; in nuclei the distance do not allow a clear detection of the rearranged chr. #16
dJ1179J13 (16p)+   CBFBF (16q)	M4eo-ANLL patien [inv(16) case 1]	OK in metaphases; in nuclei the distance do not allow a clear detection of the rearranged chr. #16

home

YAC

WCP

PCPs

TUMORS

ALPHOIDS

MOUSE