Immunoglobulin genes IGH (14q32.33) in normal cells   Atlas IGH

 Primers (5' -> 3')  Clone




dJ998D24 From 337bp upstream of the IGHA1 transmembrane exon to 5471bp upstream of the most proximal D gene (D7-27) located at 14q32.3. Information from Tim Poulsen; see the
location (Figure)

 (a very faint signal at 15q11.2 *)

It contains Variable regions; do not contain JH or Constant regions (Antonino Neri, personal communication;

  • from 1996-2015bp of seq X97051
dJ1179A6  chimeric: 14q32.33 +15q11.2 *
dJ826O13  chimeric: 14q32.33 +15q11.2 *
dJ829D3  chimeric: 14q32.33 +15q11.2 *+8
dJ872M24  chimeric: 14q32.33 +15q11.2 *
 * The signal at 15q12 is due to IGHV and IGHD orphons present at this site [Pallares N. et al., Exp. Clin. Immunogenet. 16, 36-60 (1999); Ruiz M. et al., Exp. Clin. Immunogenet. 16, 173-184 (1999)]

For details see the paper Poulsen TS, Silahtaroglu AN, Gisselo CG, Gaarsdal E, Rasmussen T, Tommerup N, Johnsen HE: Detection of illegitimate rearrangement within the immunoglobulin locus on 14q32.3 in B-cell malignancies using end-sequenced probes. Genes Chromosomes Cancer. 2001 Nov;32(3):265-74..


See also: