HLA5, HLA 7:
Likely originated from a rearrangement involving three HyA chromosomes. The centromere of HyA12 was inactivated.
HLA6:
It is identical to the ancestral form, but in opposite orientation with respect to the one reported by Jauch et al. (1990). This change to meet the orientation of the identical corresponding chromosome in NLE (Roberto et al. 2007).
Jauch, A., Daumer, C., Lichter, P., Murken, J., Schroeder-Kurth, T., and Cremer, T. 1990. Chromosomal in situ suppression hybridization of human gonosomes and autosomes and its use in clinical cytogenetics. Hum. Genet. 85: 145-150.
Roberto, R., Capozzi, O., Wilson, R.K., Mardis, E.R., Lomiento, M., Tuzun, E., Cheng, Z., Mootnick, A.R., Archidiacono, N., Rocchi, M. et al. 2007. Molecular refinement of gibbon genome rearrangement. Genome Res. 17: 249-257.