Prostate cancer fusion genes

(Tomlins et al., 2005. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648).

TMPRSS2 (21q22.3)/ETV1 (7p21.2) fusion
or
TMPRSS2 (21q22.3)/ERG (21q22.3) fusion

Probes for TMPRSS2: (chr21:41,758,350-41,801,948) (UCSC)

RP11-709L15 (chr21:41,662,261-41,827,891)
and fosmids:
G248P89444D12 (chr21:41,805,457-41,845,239)
G248P800876A1 (chr21:41,837,299-41,876,320)
G248P8239C5 (chr21:41,881,461-41,926,084)


Probes for ERG: (chr21:38,675,671-38,995,488):

RP11-476D17 (chr21:38,604,838-38,785,541) (UCSC)


Probes for ETV1: (chr7:13,897,382-13,995,289) (UCSC March 2006):

RP11-124L22
(chr7:13,834,820-13,986,205) (UCSC March 2006)
RP11-708O1 (chr7:13,834,919-14,027,777) (UCSC March 2006)

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