HyA13 and HyA14:
These inversion was previously undetected because of the limits of the painting technique.

HyA20:
Misceo et al. (2005) showed that the Hominoidea ancestral chromosome was acrocentric, therefore the Hylobatidae ancestral chromosome was a submetacentric chromosome originated from a pericentric inversion, as indicated in the Figure. It is worth noting that inversions, with breakpoints in the same region, occurred independently in the mouse and rat ancestor, in the Hylobatidae Ancestor, in orangutan, and in the ancestor of African apes and humans.

HyA26 – HyA27:
In agreement with Muller et al. (2003).

Misceo, D., Cardone, M.F., Carbone, L., D'Addabbo, P., de Jong, P.J., Rocchi, M., and Archidiacono, N. 2005. Evolutionary history of chromosome 20. Mol. Biol. Evol. 22: 360-366.

Muller, S., Hollatz, M., and Wienberg, J. 2003. Chromosomal phylogeny and evolution of gibbons (Hylobatidae). Hum. Genet. 113: 493-501.

back