Legend:
HLA karyotype showing the synteny block correspondence with the human genome. Internal red numbers indicate the human corresponding chromosome. Blue and red arrows indicate concordant (blue) and inverse (red) sequence polarity (orientation) with respect to humans. Black numbers (chromosome) followed by a letter (BAC), on the right, indicate specific BACs (Supplemental Table ST1). Breakpoints in HLA are indicated by red bars (Supplemental Table ST2). Break occurred in HyA are represented by green bars (Supplemental table ST4). :: stands for breakage and reunion in HLA and/or HyA, and the most proximal clones are reported. Rearrangements in HSA generate seemingly breaks in HLA. These apparent breaks are indicated as clones facing each other (3B/3M on HLA4p, for instance).