PhD program in
  Genetics and Molecular and Structural Evolution  
Coordinated by Prof. Mariano Rocchi

  Structural and evolutionary aspects of gut and liver in vertebrates

  D.Ferri, E.Liquori, M.Mastrodonato, G.Scillitani

1.    Comparative histology of vertebrate digestive system: functional and evolutionary aspects;
2.    Gastric-juice secreting cells: evolution and diversity;
3.    Glycohistochemistry of gastrointestinal mucins;
4.    Immunohistochemistry and immunocytochemistry of aquaporins in normal and pathologic hepatogastric system;
5.    Liver regeneration: histochemical and zonal ultrastructural aspects;
6.    Hepatic steatosis: qualitative and quantitative analysis in pathologic and experimental conditions.

Published papers (selection) (click to download the pdf)

Liquori GE, Mastrodonato M, Rossi R, Scillitani G, Gena P, Portincasa P, Calamita G, Ferri D: Altered membrane glycoprotein targeting in cholestatic hepatocytes. European Journal of Clinical Investigation 40:393-400 (2010)
Corcelli A, Saponetti MS, Zaccagnino P, Lopalco P, Mastrodonato M, Liquori GE, Lorusso M: Mitochondria isolated in nearly isotonic KCl buffer: Focus on cardiolipin and organelle morphology. Biochimica et Biophysica Acta - Biomembranes 1798:681-687 (2010)
Scillitani G, Mastrodonato M, Liquori GE, Ferri D: Co-distribution of glycoconjugates and H+, K+-ATPase in the parietal cells of the Greater Horseshoe Bat, Rhinolophus ferrumequinum (Schreber, 1774). Zoological Science 27:433-439 (2010)Liquori GE, Calamita G, Cascella D, Mastrodonato M, Portincasa P, Ferri D: An innovative methodology for the automated morphometric and quantitative estimation of liver steatosis. Histol Histopathol 24:49-60 (2009)
Mastrodonato M, Calamita G, Rossi R, Scillitani G, Liquori GE, Ferri D: Expression of H+,K+-ATPase and glycopattern analysis in the gastric glands of Rana esculenta. Journal of Histochemistry and Cytochemistry 57:215-225 (2009)
Calamita G, Ferri D, Gena P, Carreras FI, Liquori GE, Portincasa P, Marinelli RA, Svelto M: Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis. Am J Physiol-Gastro Liver Physiol 295:G682-G690 (2008)
Scillitani G, Liquori GE, Mastrodonato M, Ferri D: Histochemical and immunohistochemical characterization of exocrine cells in the foregut of the red-eared slider turtle, Trachemys scripta (Emydidae). Archives of Histology and Cytology 71:279-290 (2008)
Liquori GE, Mastrodonato M, Zizza S, Ferri D: Glycoconjugate histochemistry of the digestive tract of Triturus carnifex (Amphibia, Caudata). Journal of Molecular Histology 38:191-199 (2007)
Petrosillo G, Portincasa P, Grattagliano I, Casanova G, Matera M, Ruggiero FM, Ferri D, Paradies G: Mitochondrial dysfunction in rat with nonalcoholic fatty liver. Involvement of complex I, reactive oxygen species and cardiolipin. Biochimica et Biophysica Acta - Bioenergetics 1767:1260-1267 (2007)
Scillitani G, Zizza S, Liquori GE, Ferri D: Lectin histochemistry of gastrointestinal glycoconjugates in the greater horseshoe bat, Rhinolophus ferrumequinum (Schreber, 1774). Acta Histochemica 109:347-357 (2007)
Calamita G, Gena P, Meleleo D, Ferri D, Svelto M: Water permeability of rat liver mitochondria: A biophysical study. Biochimica et Biophysica Acta - Biomembranes 1758:1018-1024 (2006)
Van Erpecum KJ, Wang DQH, Moschetta A, Ferri D, Svelto M, Portincasa P, Hendrickx JJ, Schipper M, Calamita G: Gallbladder histopathology during murine gallstone formation: Relation to motility and concentrating function. Journal of Lipid Research 47:32-41 (2006)
Calamita G, Ferri D, Bazzini C, Mazzone A, Botta' G, Liquori GE, Paulmichl M, Portincasa P, Meyer G, Svelto M: Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium. Biology of the Cell 97:415-423 (2005)
Calamita G, Ferri D, Gena P, Liquori GE, Cavalier A, Thomas D, Svelto M: The inner mitochondrial membrane has aquaporin-8 water channels and is highly permeable to water. Journal of Biological Chemistry 280:17149-17153 (2005)
Liquori GE, Zizza S, Mastrodonato M, Scillitani G, Calamita G, Ferri D: Pepsinogen and H,K-ATPase mediate acid secretion in gastric glands of Triturus carnifex (Amphibia, Caudata). Acta Histochemica 107:133-141 (2005)
Ferri D, Moro L, Mastrodonato M, Capuano F, Marra E, Liquori GE, Greco M: Ultrastructural zonal heterogeneity of hepatocytes and mitochondria within the hepatic acinus during liver regeneration after partial hepatectomy. Biology of the Cell 97:277-288 (2005)
Liquori GE, Caroppo R, Mastrodonato M, Scillitani G, Ferri D: Co-secretion of soluble caveolin-1 and pepsinogen in the oesophagus of the red-legged frog Rana aurora aurora. Acta Histochemica 106:21-27 (2004)
Ferri D, Mazzone A, Liquori GE, Cassano G, Svelto M, Calamita G: Ontogeny, distribution, and possible functional implications of an unusual aquaporin, AQP8, in mouse liver. Hepatology 38:947-957 (2003)
Liquori GE, Scillitani G, Mastrodonato M, Ferri D: Histochemical investigations on the secretory cells in the oesophagogastric tract of the Eurasian green toad, Bufo viridis. Histochemical Journal 34:517-524 (2002)