PhD program in
  Genetics and Molecular and Structural Evolution  
Coordinated by Prof. Mariano Rocchi

  Retrotransposons in Drosophila as insulators


Functional analysis of Drosophila retrotransposons as source of powerful inter-specific insulator sequences for the development of integrating vectors that are able to escape to position effects and gene-toxicity in gene therapy trials.

Published papers (selection) (click to download the pdf)

De Grassi A, Caggese C, D'Elia D, Lanave C, Pesole G, Saccone C: Evolution of nuclearly encoded mitochondrial genes in Metazoa. Gene 354:181-188 (2005)