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NUCLEOTIDE DATABASES

NCBI's sequence databases accept genome data from sequencing projects from around the world and serve as the cornerstone of bioinformatics research.
 

GenBank:

An annotated collection of all publicly available nucleotide and amino acid sequences.

 

EST database:

A collection of expressed sequence tags, or short, single-pass sequence reads from mRNA (cDNA).

 

GSS database:

A database of genome survey sequences, or short, single-pass genomic sequences.

 

HomoloGene:

A gene homology tool that compares nucleotide sequences between pairs of organisms in order to identify putative orthologs.

 

HTG database:

A collection of high-throughput genome sequences from large-scale genome sequencing centers, including unfinished and finished sequences.

 

SNPs database:

A central repository for both single-base nucleotide substitutions and short deletion and insertion polymorphisms.

 

RefSeq:

A database of non-redundant reference sequences standards, including genomic DNA contigs, mRNAs, and proteins for known genes. Multiple collaborations, both within NCBI and with external groups, support our data-gathering efforts.

 

STS database:

A database of sequence tagged sites, or short sequences that are operationally unique in the genome.

 

UniSTS:

A unified, non-redundant view of sequence tagged sites (STSs).

 

UniGene:

A collection of ESTs and full-length mRNA sequences organized into clusters, each representing a unique known or putative human gene annotated with mapping and expression information and cross-references to other sources.

 
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